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For weight loss: The doses can be higher The goals focus on reducing body weight and improving metabolic health It is used even in people without diabetes For diabetes: The focus is on improving blood sugar Weight loss is an added benefit but not the primary goal Because of these differences, healthcare providers choose the dose and plan based on each persons medical needs
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Reaching Full Dose Weight loss continues steadily
However, sustained high levels of circulating insulin may conversely exert a negative influence on cognitive function, due to prolonged peripheral hyperinsulinemia down-regulates insulin receptors at the blood-brain barrier (BBB) and reduces insulin transport into the brain, leading to brain insulin resistance (BIR) (1719)
Because stopping semaglutide typically leads to some degree of weight regain , many people continue treatment to maintain their results and protect against weight-related health risks
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